发明名称 Multivalent fibronectin based scaffold domain proteins
摘要 The present invention relates to multivalent polypeptides comprising at least two fibronectin scaffold domains connected via a polypeptide linker. The invention also relates to multivalent polypeptides for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins.
申请公布号 US8728483(B2) 申请公布日期 2014.05.20
申请号 US201213533382 申请日期 2012.06.26
申请人 CAMPHAUSEN RAY;FURFINE ERIC;CARVAJAL IRVITH M.;MARSH H. NICHOLAS;GOTTARDIS MARCO;CARBONI JOAN;ATTAR RICARDO;BRISTOL-MYERS SQUIBB COMPANY 发明人 CAMPHAUSEN RAY;FURFINE ERIC;CARVAJAL IRVITH M.;MARSH H. NICHOLAS;GOTTARDIS MARCO;CARBONI JOAN;ATTAR RICARDO
分类号 A61K38/39;A61K47/48;C07K14/435;C07K14/705;C07K14/78 主分类号 A61K38/39
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