发明名称 |
Multivalent fibronectin based scaffold domain proteins |
摘要 |
The present invention relates to multivalent polypeptides comprising at least two fibronectin scaffold domains connected via a polypeptide linker. The invention also relates to multivalent polypeptides for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins. |
申请公布号 |
US8728483(B2) |
申请公布日期 |
2014.05.20 |
申请号 |
US201213533382 |
申请日期 |
2012.06.26 |
申请人 |
CAMPHAUSEN RAY;FURFINE ERIC;CARVAJAL IRVITH M.;MARSH H. NICHOLAS;GOTTARDIS MARCO;CARBONI JOAN;ATTAR RICARDO;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
CAMPHAUSEN RAY;FURFINE ERIC;CARVAJAL IRVITH M.;MARSH H. NICHOLAS;GOTTARDIS MARCO;CARBONI JOAN;ATTAR RICARDO |
分类号 |
A61K38/39;A61K47/48;C07K14/435;C07K14/705;C07K14/78 |
主分类号 |
A61K38/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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