发明名称 |
Selection and characterization of novel plant-derived recombinant human interferons with broad spectrum activity |
摘要 |
Methods to derive novel hybrid type 1 interferons that are broadly active against highly pathogenic viruses of biodefense significance are described. Libraries of hybrid interferon genes were produced using gene shuffling, the proteins were expressed, and screened for activity against viruses of interest. Sequences of several broadly active hybrid interferons are described. |
申请公布号 |
US8729236(B2) |
申请公布日期 |
2014.05.20 |
申请号 |
US201213478330 |
申请日期 |
2012.05.23 |
申请人 |
PADGETT HAL S.;VOJDANI FAKHRIEH S.;VAEWHONGS ANDREW A. |
发明人 |
PADGETT HAL S.;VOJDANI FAKHRIEH S.;VAEWHONGS ANDREW A. |
分类号 |
C07K14/52 |
主分类号 |
C07K14/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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