AGENTES PARA TERAPIA E/OU MELHORA DE COAGULAÇÃO INTRAVASCULAR DISSEMINADA, PARA REDUZIR A PROBABILIDADE DE MORTE EM PACIENTES SOFRENDO DA MESMA, MÉTODOS PARA SELECIONAR PACIENTES, E, PARA TRATAR E/OU MELHORAR COAGULAÇÃO INTRAVASCULAR DISSEMINADA

摘要

It is an object of the present invention to provide a therapeutically effective agent for therapy and/or improvement of DIC, or a method for treating and/or improving DIC. The present invention provides an agent for therapy and/or improvement of disseminated intravascular coagulation comprising thrombomodulin as an active ingredient, which is administered to antithrombin-reduced patients having a low plasma antithrombin activity of less than 50%.