发明名称 |
Compositions and methods for promoting the generation of PDX1+ pancreatic cells |
摘要 |
Certain embodiments disclosed herein are directed to a method of producing pancreatic cells or pancreatic cell precursors by exposing human embryonic stem cells to an effective amount of at least one compound listed in Table I to differentiate the human embryonic stem cells into the pancreatic cells or the pancreatic cell precursors. Kits and pancreatic cell lines produced using the methods are also described. |
申请公布号 |
US8728812(B2) |
申请公布日期 |
2014.05.20 |
申请号 |
US20090989284 |
申请日期 |
2009.04.22 |
申请人 |
CHEN SHUIBING;MELTON DOUGLAS A.;BOROWIAK MALGORZATA;LAMENZO JULIA;SCHREIBER STUART L.;PENG LEE F.;DAVIDOW LANCE;LAM KELVIN;RUBIN LEE L.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE GENERAL HOSPITAL CORPORATION |
发明人 |
CHEN SHUIBING;MELTON DOUGLAS A.;BOROWIAK MALGORZATA;LAMENZO JULIA;SCHREIBER STUART L.;PENG LEE F.;DAVIDOW LANCE;LAM KELVIN;RUBIN LEE L. |
分类号 |
C12N5/00;C12N5/02;C12N5/071 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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