| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to formula (I) compounds, where n stands for integer number from 1 to 10 including; m stands for integer number from 0 to 5 including; k stands for integer number from 0 to 5 including; p stands for integer number from 0 to 4 including; Rstands for C(O)NHOH; Rstands for hydrogen atom; lower alkyl or -OR, where Rrepresents lower alkyl; Rstands for hydrogen atom; lower alkyl or -OR, where Rrepresents lower alkyl; Rstands for hydrogen atom. Invention also relates to their pharmaceutical composition, inhibiting activity of histone deacetylase, which contains said compounds, and to method of inhibiting deacetylase activity.EFFECT: compounds of formula(I) as deacetylase inhibitors.18 cl, 9 dwg, 7 tbl, 4 ex |
