| 摘要 |
FIELD: chemistry.SUBSTANCE: claimed invention relates to biocompatible polyisocyanate macromer or mixture of macromers for application as glue or sealant for internal application, represented by formula:, where f equals two or more; a in the range from 1 to 5 and Rrepresents, where d is in the range from 0 to 5 and c can be in the range from 1 to 100; Rrepresents, where Rrepresents linear or branched residue of water-soluble polymer, which forms ester bonds with Rand urethane bonds with R, when a equals one or more; and Rrepresents linear or branched organic residue, which contains two or more carboxylate terminal groups, and x gives the number of repeating Rand is in the range 2?x?6. Also described are biocompatible elastic gel, obtained by polymerisation of said macromer, composition, applicable for medicine, and method of internal wound closing.EFFECT: creation of glue or sealant for internal application, preserving ability for manipulations and smoothing, which fills internal sinuses and empty spaces, penetrates and tightly fits cavities and pores of tissue before hardening or setting, and is biologically decomposable.9 cl, 3 tbl, 3 ex |
