发明名称 POLYPEPTIDES HAVING NEUTROPHIL STIMULATING ACTIVITY
摘要 Neutrophil attracting and activating factors that may already exist in normal cells are located. The invention provides (a) a polypeptide consisting of the amino acid sequence of SEQ ID NO:4 or 5; (b) a polypeptide consisting of the amino acid sequence which shares at least 90% identity with the amino acid sequence of SEQ ID NO: 4 or 5 and having neutrophil stimulating activity; or (c) a polypeptide consisting of an amino acid sequence derived from the amino acid sequence of SEQ ID NO: 4 or 5 by deletion, substitution, insertion or addition of one or more amino acids and having neutrophil stimulating activity, wherein an N-terminus of said polypeptide is modified by formylation, acetylation or methylation. The invention also provides an antibody specific to said polypeptide, a method utilizing said polypeptide, and a kit comprising said polypeptide.
申请公布号 CA2723031(C) 申请公布日期 2014.05.20
申请号 CA20012723031 申请日期 2001.03.06
申请人 JAPAN TOBACCO INC. 发明人 MUKAI, HIDEHITO;NISHI, YOSHISUKE;MUNEKATA, EISUKE
分类号 C07K14/80;A61K38/00;C07K14/47;C07K14/52;C07K16/18;C07K16/24;C12N15/12;G01N33/68 主分类号 C07K14/80
代理机构 代理人
主权项
地址