| 摘要 |
<p>Process for removal of the amino protective group of a N-acylated {(1S,4R)-4- [2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl}methanol of formula (II) where R = H or a (C<SUB>1</SUB>-C<SUB>4</SUB>)-alkyl, using an inorganic base in a mixture of water and alcohol, to yield abacavir or its salts. The process proceeds very fast and the product can be obtained in high yield and purity.</p> |
