发明名称 NEW PROCESS FOR THE SYNTHESIS OF (2E)-3-(3,4-DIMETHOXYPHENYL)PROP-2-ENENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID
摘要 The present invention relates to a novel method for synthesizing (2E)-3-(3,4-dimethoxyphenyl) prop-2-en-nitrile and application thereof in synthesis of ivabradine and addition salts thereof with pharmaceutically acceptable acid. A compound of the present invention is presented by chemical formula (I).
申请公布号 KR20140059731(A) 申请公布日期 2014.05.16
申请号 KR20130133365 申请日期 2013.11.05
申请人 LES LABORATOIRES SERVIER 发明人 CARRANZA MARIA DEL PILAR;GARCIA ARANDA MARIA ISABEL;GONZALEZ JOSE LORENZO;SANCHEZ FREDERIC
分类号 C07C253/32;B01J23/44;C07C255/34 主分类号 C07C253/32
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