发明名称 |
NEW PROCESS FOR THE SYNTHESIS OF (2E)-3-(3,4-DIMETHOXYPHENYL)PROP-2-ENENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID |
摘要 |
The present invention relates to a novel method for synthesizing (2E)-3-(3,4-dimethoxyphenyl) prop-2-en-nitrile and application thereof in synthesis of ivabradine and addition salts thereof with pharmaceutically acceptable acid. A compound of the present invention is presented by chemical formula (I). |
申请公布号 |
KR20140059731(A) |
申请公布日期 |
2014.05.16 |
申请号 |
KR20130133365 |
申请日期 |
2013.11.05 |
申请人 |
LES LABORATOIRES SERVIER |
发明人 |
CARRANZA MARIA DEL PILAR;GARCIA ARANDA MARIA ISABEL;GONZALEZ JOSE LORENZO;SANCHEZ FREDERIC |
分类号 |
C07C253/32;B01J23/44;C07C255/34 |
主分类号 |
C07C253/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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