COMPOSITIONS AND METHODS FOR MODULATING CELL SIGNALING
摘要
The present invention provides growth factor-directed agents (GDAs), which act as either antagonists or agonists of cell signaling, particularly in the TGF-beta and related extracellular matrix signaling pathways. Such GDAs include monoclonal antibodies, fusion proteins and novel polypeptide compositions and/or conjugates of these compositions.
申请公布号
WO2014074532(A2)
申请公布日期
2014.05.15
申请号
WO2013US68613
申请日期
2013.11.06
申请人
SCHOLAR ROCK INC.;CHILDREN'S MEDICAL CENTER CORPORATION
发明人
SPRINGER, TIMOTHY, ALAN;ZON, LEONARD, IRA;MAHANTHAPPA, NAGESH, K.