| 发明名称 |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BONE METASTASES |
| 摘要 |
The present disclosure relates to methods and pharmaceutical compositions for the treatment of bone metastases. In particular, the present disclosure relates to an agent selected from the group consisting of an anti-ROB04 antibody, an anti-ROB04 aptamer, a ROB04 decoy polypeptide, an inhibitor of ROB04 expression for use in a method for preventing or treating bone metastases in a subject in need thereof. |
| 申请公布号 |
WO2014072416(A1) |
申请公布日期 |
2014.05.15 |
| 申请号 |
WO2013EP73284 |
申请日期 |
2013.11.07 |
| 申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);UNIVERSITÉ CLAUDE BERNARD - LYON 1 |
发明人 |
CLEZARDIN, PHILIPPE;ECKEL, BÉNÉDICTE;DIAZ-LATOUD, CHANTAL;CLEMENT-DEMANGE, LISE |
| 分类号 |
C12N15/113;A61P35/04;C07K16/28;C07K16/30;G01N33/574 |
主分类号 |
C12N15/113 |
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