PERIOSTIN EXPRESSION INHIBITOR COMPRISING SHIKONIN DERIVATIVE

摘要

[Problem] To provide a periostin inhibitor that inhibits the activity of periostin, an agent for treating atopic dermatitis with high periostin expression, an anti-inflammatory agent for periostin-related inflammation, and an agent for treating or preventing keloid or hypertrophic scar. [Solution] A periostin inhibitor, an agent for treating atopic dermatitis with high periostin expression, an anti-inflammatory agent for periostin-related inflammation, and an agent for treating or preventing keloid or hypertrophic scar, each comprising as an active ingredientβ-hydroxyisovalerylshikonin, a pharmaceutically acceptable salt ofβ-hydroxyisovalerylshikonin or a pharmaceutically acceptable solvate ofβ-hydroxyisovalerylshikonin.