Crystal Form of Quinoline Compound and Process for its Production

摘要

C:/NRPonblDCC/REC382J700 LDOC-M IATE * KERGEFORMAT A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) 5 represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.