发明名称 |
METHODS OF MODULATING SMYD3 FOR TREATMENT OF CANCER |
摘要 |
The present invention features a method for determining the methyltransferase activity of a polypeptide and screening for modulators of methyltransferase activity, more particularly for modulators of the methylation of retinoblastoma by SMYD3. The invention further provides a method or pharmaceutical composition for prevention or treating of colorectal cancer, hepatocellular carcinoma, bladder cancer and/or breast cancer using a modulator so identified. |
申请公布号 |
US2014134637(A1) |
申请公布日期 |
2014.05.15 |
申请号 |
US201113092770 |
申请日期 |
2011.04.22 |
申请人 |
NAKAMURA YUSUKE;FURUKAWA YOICHI;HAMAMOTO RYUJI;NAKATSURU SHUICHI;ONCOTHERAPY SCIENCE, INC. |
发明人 |
NAKAMURA YUSUKE;FURUKAWA YOICHI;HAMAMOTO RYUJI;NAKATSURU SHUICHI |
分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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