发明名称 |
METHODS OF TREATING NEUROENDOCRINE TUMORS USING FRIZZLED-BINDING AGENTS |
摘要 |
Novel methods of treating neuroendocrine tumors are provided. In one embodiment, the method comprises administering to a subject in need thereof a therapeutically effective dose of a Wnt antagonist. In one embodiment, the Wnt antagonist is an anti-FZD antibody. In another embodiment, the Wnt antagonist is a soluble FZD receptor polypeptide. In a further embodiment, the Wnt antagonist is an anti-Wnt antibody. |
申请公布号 |
US2014134159(A1) |
申请公布日期 |
2014.05.15 |
申请号 |
US201314059918 |
申请日期 |
2013.10.22 |
申请人 |
ONCOMED PHARMACEUTICALS, INC. |
发明人 |
STAGG ROBERT JOSEPH;DUPONT JAKOB |
分类号 |
C07K16/30;A61K39/395;A61K45/06 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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