发明名称 |
METHOD FOR ACETATE CONSUMPTION DURING ETHANOLIC FERMENTATION OF CELLULOSIC FEEDSTOCKS |
摘要 |
The present invention provides for novel metabolic pathways to detoxify biomass- derived acetate via metabolic conversion to ethanol, acetone, or isopropanol. More specifically, the invention provides for a recombinant microorganism comprising one or more native and/or heterologous enzymes that function in one or more first engineered metabolic pathways to achieve: (1) conversion of acetate to ethanol; (2) conversion of acetate to acetone; or (3) conversion of acetate to isopropanol; and one or more native and/or heterologous enzymes that function in one or more second engineered metabolic pathways to produce an electron donor used in the conversion of acetate to less inhibitory compounds; wherein the one or more native and/or heterologous enzymes is activated, upregulated, or downregulated. |
申请公布号 |
WO2014074895(A2) |
申请公布日期 |
2014.05.15 |
申请号 |
WO2013US69266 |
申请日期 |
2013.11.08 |
申请人 |
MASCOMA CORPORATION |
发明人 |
ZELLE, RINTZE MEINDERT;SHAW IV, ARTHUR J.;VAN DIJKEN, JOHANNES PIETER |
分类号 |
C12N9/04;C12N9/02;C12P7/10 |
主分类号 |
C12N9/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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