THERAPEUTIC COMPOUNDS AND COMPOSITIONS AND THEIR USE AS PKM2 MODULATORS
摘要
Compositions comprising compounds of general formula (I) that modulate pyruvate kinase are described herein. Also described herein are methods of using the compounds that modulate pyruvate kinase in the treatment of diseases.
申请公布号
WO2014074848(A1)
申请公布日期
2014.05.15
申请号
WO2013US69193
申请日期
2013.11.08
申请人
AGIOS PHARMACEUTICALS, INC.
发明人
POPOVICI-MULLER, JANETA;SAUNDERS, JEFFREY, O.;ZAHLER, ROBERT;CIANCHETTA, GIOVANNI