发明名称 |
SELECTIVE TARGETING OF CANCER STEM CELLS |
摘要 |
<p>Aspects of the invention relate to methods and related compositions for preferentially targeting cancer stem cells. In some embodiments, the methods utilize PKC-α/FRA1 pathway inhibitors to target carcinoma cells. Also provided are methods for identifying a candidate compound for selectively inhibiting growth of cancer stem cell, and methods for obtaining cells that have undergone an epithelial to mesenchymal transition.</p> |
申请公布号 |
WO2014074805(A1) |
申请公布日期 |
2014.05.15 |
申请号 |
WO2013US69121 |
申请日期 |
2013.11.08 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
TAM, WAI, LEONG;WEINBERG, ROBERT, A. |
分类号 |
C12N5/09;A61P35/00;C12N5/095 |
主分类号 |
C12N5/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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