发明名称 |
METHOD FOR CELLULAR RNA EXPRESSION |
摘要 |
<p>The present invention relates to expressing RNA in cells and, in particular, enhancing viability of cells in which RNA is to be expressed. Specifically, the present invention provides methods for expressing RNA in cells comprising the steps of preventing engagement of IFN receptor by extracellular IFN and inhibiting intracellular IFN signalling in the cells. Thus, preventing engagement of IFN receptor by extracellular IFN and inhibiting intracellular IFN signalling in the cells allows repetitive transfer of RNA into the cells.</p> |
申请公布号 |
CA2890529(A1) |
申请公布日期 |
2014.05.15 |
申请号 |
CA20132890529 |
申请日期 |
2013.11.07 |
申请人 |
UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERT-UNIVERSITAT MAINZ;BIONTECH AG;TRON-TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ GEMEINNUTZIGE GMBH |
发明人 |
SAHIN, UGUR;BEISSERT, TIM;POLEGANOV, MARCO;HERZ, STEPHANIE;KOSTE, LARS |
分类号 |
C12N15/67;C12N15/68;C12N15/69 |
主分类号 |
C12N15/67 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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