发明名称 CRYSTALLINE FORMS OF (1S)-1-[5-({3-[(2-METHYLPYRIDIN-3-YL)OXY]-5-(PYRIDIN-2-YLSULFANYL)PYRIDIN-2-YL}AMINO)-1,2,4-THIADIAZOL-3-YL]ETHANE-1,2-DIOL
摘要 <p>The present invention relates to crystalline polymorph forms of (1S)-1-[5-({3-[(2-methylpyridin-3-yl)oxy]-5-(pyridin-2-ylsulfanyl)pyridin-2-yl}amino)-1,2,4-thiadiazol-3-yl]ethane-1,2-diol, to pharmaceutical compositions comprising such crystalline polymorph forms, and to processes for preparing them. The invention further relates to methods of treatment of diabetes related disorders comprising administering such solid-state forms or compositions thereof to a subject, and to use of such crystalline polymorph forms in the manufacture of medicaments.</p>
申请公布号 CA2890852(A1) 申请公布日期 2014.05.15
申请号 CA20132890852 申请日期 2013.11.08
申请人 ARRAY BIOPHARMA INC.;AMGEN INC. 发明人 ASSELIN, SYLVIE;BRETT, LISA;CHEN, YING;CORSON, DONALD T.;COSBIE, ANDREW;FARRELL, ROBERT;GUNAWARDANA, INDRANI W.;HUANG, JINKUN;LANE, JONATHAN W.;LEI, DENNIS;LINDEMANN, CHRISTOPHER M.;LUU, VAN;MANNILA, CORALEE G.;MILBURN, ROBERT;MORRISON, HENRY;TAN, HELMING;TEDROW, JASON;WATSON, DANIEL J.
分类号 C07D417/14;A61K31/444;A61P3/10 主分类号 C07D417/14
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