IN VITRO CAPTURE AND ANALYSIS OF CIRCULATING TUMOR CELLS
摘要
This invention provides methods and compositions for capturing circulating tumor cells (CTCs) as well as various divergent CTC phenotypes using seprase-specific affinity reagents. Methods of analyzing CTCs and assessing their metastatic potential in vivo and in vitro are also disclosed.
申请公布号
WO2014072465(A1)
申请公布日期
2014.05.15
申请号
WO2013EP73381
申请日期
2013.11.08
申请人
ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG
发明人
MARTIN, GEORGE, A.;SOPER, STEVEN;WITEK, MAKGORZATA;YEH, JEN JEN