| 发明名称 |
RNA antagonist compounds for the inhibition of Apo-B100 expression |
| 摘要 |
Short oligonucleotides directed against the Apo-B100 gene are provided for modulating the expression of Apo-B100. Methods of using these compounds for modulation of Apo-B100 expression and for the treatment of diseases associated with Apo-B100 expression are provided. The oligonucleotides comprise deoxyribonucleosides and locked nucleic acids. |
| 申请公布号 |
AU2008228243(B2) |
申请公布日期 |
2014.05.15 |
| 申请号 |
AU20080228243 |
申请日期 |
2008.03.19 |
| 申请人 |
SANTARIS PHARMA A/S |
发明人 |
ROSENBOHM, CHRISTOPH;STRAARUP, ELLEN MARIE;HANSEN, BO;HANSEN, HENRIK FRYDENLUND |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
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