发明名称 ANTI-ANDROGEN PEPTIDE AND USE THEREOF IN CANCER TREATMENT
摘要 PROBLEM TO BE SOLVED: To provide a native, site specifically mutated, and synthetic peptide comprising portions of human androgen receptor used in treatment of prostate cancer and breast cancer, and a composition thereof.SOLUTION: Provided is an isolated or purified or partially purified, peptide-derived molecule represented by the general formula (S1), capable of inhibiting or preventing interaction between androgen receptor (AR) and SH3 domain of tyrosine kinase Src. The peptide is used in medicine, particularly as an anti-tumor agent.
申请公布号 JP2014087363(A) 申请公布日期 2014.05.15
申请号 JP20140001333 申请日期 2014.01.08
申请人 CANCER RESEARCH TECHNOLOGY LTD 发明人 AURICCHIO FERDINANDO;ANTIMO MIGLIACCIO
分类号 C12N15/09;A61K9/10;A61K9/127;A61K9/51;A61K38/00;A61K39/00;A61K45/00;A61K47/44;A61P35/00;A61P43/00;C07K14/705;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10 主分类号 C12N15/09
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