发明名称 |
COMPOSITIONS OF ROTIGOTINE, DERIVATIVES THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS OF ROTIGOTINE OR ITS DERIVATIVE |
摘要 |
<p>The disclosure provides a composition comprising rotigotine or a pharmaceutically acceptable salt thereof; at least one poly(lactide-co-glycolide) (PLGA); and at least one fatty acid, wherein the at least one fatty acid is at least 0.5% in weight relative to the total weight of the composition. The composition as disclosed herein has significantly reduced burse release effect. The disclosure also provides a method of treating Parkinson's disease comprising administering an effective amount of the composition as disclosed to a subject in need thereof.</p> |
申请公布号 |
EP2642993(A4) |
申请公布日期 |
2014.05.14 |
申请号 |
EP20110843219 |
申请日期 |
2011.11.25 |
申请人 |
SHAN DONG LUYE PHARMACEUTICAL CO., LTD. |
发明人 |
LI , YOUXIN;WANG, AIPING;LIU, WANHUI;SUN, KAOXIANG;LI , JUN;SUN, LIFANG |
分类号 |
A61K31/381;A61K9/14;A61K9/16;A61K9/50;A61K47/34;A61P25/16 |
主分类号 |
A61K31/381 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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