<p>Molecular dynamics (MD) simulation on the three-dimensional structure of Candida anrtarctica lipase B revealed two hitherto unknown lids with a marked mobility, and this discovery was used to design lipolytic enzyme variants with increased lipolytic enzyme activity, like variants in which residue 147 has been altered.</p>
申请公布号
EP2264157(B1)
申请公布日期
2014.05.14
申请号
EP20100182266
申请日期
2007.11.26
申请人
NOVOZYMES A/S
发明人
DE MARIA, LEONARDO;BRASK, JESPER;SKJØT, MICHAEL;PATKAR, SHAMKANT, ANANT;BORCH, KIM;SVENDSEN, ALLAN