发明名称 |
SUPPRESSION OF CANCER GROWTH AND METASTASIS USING NORDIHYDROGUAIARETIC ACID DERIVATIVES WITH METABOLIC MODULATORS |
摘要 |
<p>Disclosed is a composition comprising a derivative of NDGA and at least one metabolic modulator. The composition can be in a unit dose form or kit. The composition can comprise at least two metabolic modulators. Also disclosed are methods for achieving cytotoxicity, particularly of rapidly dividing cells such as cancer, by administering a composition of the invention. In various embodiments of the invention subjects with cancer achieve prolonged survival and/or diminution in the size of their malignancies and cancer metastasis.</p> |
申请公布号 |
EP2240168(B1) |
申请公布日期 |
2014.05.14 |
申请号 |
EP20090701300 |
申请日期 |
2009.01.08 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
HUANG, RU CHIH C.;KIMURA, KOTOHIKO |
分类号 |
A61K31/03;A61K31/045;A61K31/09;A61K31/12;A61K31/454;A61K31/519;A61K31/525;A61P35/00 |
主分类号 |
A61K31/03 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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