发明名称 |
OIL-IN-WATER EMULSIONS THAT CONTAIN NUCLEIC ACIDS |
摘要 |
This invention generally relates to cationic oil-in-water emulsions that can be used to deliver nucleic acid molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The emulsion particles have an average diameter of about 80 nm to about 180 nm, and the emulsion have an N/P ratio of at least 1.1:1. |
申请公布号 |
EP2729125(A1) |
申请公布日期 |
2014.05.14 |
申请号 |
EP20120738311 |
申请日期 |
2012.07.06 |
申请人 |
NOVARTIS AG |
发明人 |
BRITO, LUIS;CHAN, MICHELLE;GEALL, ANDREW;O'HAGAN, DEREK;SINGH, MANMOHAN |
分类号 |
A61K9/127;A61K39/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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