| 发明名称 |
1-PYRIMIDINYL- OR 1-PYRIDINYL-2-AMINO BENZIMIDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF PROTEIN KINASES FOR THE TREATMENT OF CANCER |
| 摘要 |
<p>The present invention relates to compounds useful as inhibitors of Aurora, FLT-3, or PDK1 protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the invention.</p> |
| 申请公布号 |
EP2336122(B1) |
申请公布日期 |
2014.05.14 |
| 申请号 |
EP20100185388 |
申请日期 |
2006.07.21 |
| 申请人 |
VERTEX PHARMACEUTICALS INC. |
发明人 |
BINCH, HAYLEY;MORTIMORE, MICHAEL;ROBINSON, DANIEL;STAMOS, DEAN;EVERITT, SIMON |
| 分类号 |
C07D403/04;A61K31/4439;A61K31/506;A61K31/55;A61K31/551;A61P35/00;C07D401/14;C07D403/14 |
主分类号 |
C07D403/04 |
| 代理机构 |
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