摘要 |
<p>#CMT# #/CMT# Cosmetic use of coumarin (I) and its derivatives/mixture to prevent, limit and/or stop the development of canities. #CMT# : #/CMT# Independent claims are included for: (1) a cosmetic composition comprising (I) in combination with another active agents that controls desquamating scalp and/or herbal extracts having propigmentante activity, in a medium; (2) a composition comprising (I) in combination with an agent slowing hair loss or promoting their regrowth; and (3) treatment of canities, comprises oral administration or topical application (on the zone to be treated) of a composition comprising (I). #CMT#ACTIVITY : #/CMT# Dermatological; Endocrine-Gen. #CMT#MECHANISM OF ACTION : #/CMT# Glutathione synthesis stimulator. #CMT#USE : #/CMT# (I) is useful to prevent, limit and/or stop the development of canities, to maintain and/or restore the natural pigmentation of hair and/or gray hair (claimed). The ability of (I) in repigmetation of hair was tested in human. The results showed that the lotion comprising (I) exhibited a repigmentation of white and gray hair. #CMT#ORGANIC CHEMISTRY : #/CMT# Preferred Components: (I) is encapsulated in a coating such as microspheres, nanospheres, oleosomes or nanocapsules. #CMT#ADMINISTRATION : #/CMT# Administration of (I) is oral or topical. Administration of the composition is topical on the scalp and/or areas of the skin covered with hair (all claimed). No dosage details given. #CMT#EXAMPLE : #/CMT# Typical composition comprised (in g): coumarin (0.5); propylene glycol (20); 95% ethanol (30); and water (to make up to 100).</p> |