Bi-functional compound positively charged at first pH and negatively charged at second pH, solid support comprising the bi-functional compound, and method of isolating nucleic acid using the same

摘要

Provided are a bi-functional compound that is positively charged at a first pH and negatively charged at a second pH, a solid support having the bi-functional compound immobilized thereon, and a method of isolating a nucleic acid, including: binding the bi-functional compound with a nucleic acid at a first pH and isolating the nucleic acid from the bi-functional compound at a second pH.