发明名称 |
CATIONIC OIL-IN-WATER EMULSIONS |
摘要 |
This invention generally relates to cationic oil-in-water emulsions that contain high concentrations of cationic lipids and have a defined oil:lipid ratio. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are useful for delivering negatively charged molecules, such as nucleic acid molecules to cells, and for formulating nucleic acid-based vaccines. |
申请公布号 |
EP2729124(A1) |
申请公布日期 |
2014.05.14 |
申请号 |
EP20120743273 |
申请日期 |
2012.07.06 |
申请人 |
NOVARTIS AG |
发明人 |
BRITO, LUIS;CHAN, MICHELLE;GEALL, ANDREW;O'HAGAN, DEREK;SINGH, MANMOHAN |
分类号 |
A61K9/107;A61K39/00;A61K47/06;A61K47/24 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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