Replicons of genotype 3 of hepatitis C virus (HCV) are provided. These replicons contains adaptive mutations giving rise to the HCV's capability to replicate in vitro. Methods of preparing genotype 3 replicons and methods of using these replicons to screen antiviral agents are also provided.
申请公布号
EP2729489(A1)
申请公布日期
2014.05.14
申请号
EP20120735415
申请日期
2012.07.05
申请人
GILEAD SCIENCES, INC.
发明人
DELANEY, WILLIAM, E., IV;CHENG, GUOFENG;YU, MEI;MO HONGMEI;XU, SIMINQ;CORSA, AMOREENA
