发明名称 |
Method and apparatus for identification of biological material |
摘要 |
Biological material is detected in a sample using a MALDI-MS technique (Matrix Assisted Laser Desorption and Ionization-Mass Spectroscopy). A liquid comprising the sample and a MALDI matrix material is prepared and used to form a continuous stream of the liquid. The stream is separated into successive parts to form drops, which are launched into flight, or the stream is launched into flight and then separated into drops. Drop forming techniques may be used that are known from ink jet printers. Material from the drops is ionized while in flight. Mass spectra from the ionized material of respective drops are measured. Preferably, before the drops are formed the liquid is diluted to a level where the majority of drops at most one micro-organism is present per drop. |
申请公布号 |
US8723106(B2) |
申请公布日期 |
2014.05.13 |
申请号 |
US200913059947 |
申请日期 |
2009.08.21 |
申请人 |
VAN WUIJCKHUIJSE ARJAN LAURENS;PARCHEN RENE;NEDERLANDSE ORGANSATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO |
发明人 |
VAN WUIJCKHUIJSE ARJAN LAURENS;PARCHEN RENE |
分类号 |
B01D59/44 |
主分类号 |
B01D59/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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