发明名称 |
Pyrazine derivatives and uses thereof in renal monitoring |
摘要 |
The present invention relates to pyrazine derivatives such as those represented by Formulas I and II below. X1 to X4 of the compounds of Formulas I and II may be characterized as electron withdrawing groups. In contrast, Y1 to Y4 of the compounds of Formulas I and II may be characterized as electron donating groups. Pyrazine derivatives of the present invention may be utilized in assessing renal function. In particular, an effective amount of a pyrazine derivative of the invention may be administered into a body of a patient. The pyrazine derivative that is in the body may be exposed to visible and/or infrared light to cause spectral energy to emanate from the pyrazine derivative. This emanating spectral energy may be detected and utilized to determine renal function of the patient. |
申请公布号 |
US8722685(B2) |
申请公布日期 |
2014.05.13 |
申请号 |
US201213343231 |
申请日期 |
2012.01.04 |
申请人 |
RAJAGOPALAN RAGHAVAN;DORSHOW RICHARD B.;NEUMANN WILLIAM L.;MEDIBEACON, LLC |
发明人 |
RAJAGOPALAN RAGHAVAN;DORSHOW RICHARD B.;NEUMANN WILLIAM L. |
分类号 |
A61K31/4965;C07D241/02 |
主分类号 |
A61K31/4965 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|