SURFACE-ACTIVE PHOTOSENSITISER CONSTITUTING 2-{4-[(E)-2-(4-ETHOXYPHENYL)VINYL]PHENOXY}-N,N,N-TRIMETHYLETHANAMINE BROMIDE (S-TAB)

摘要

FIELD: chemistry.SUBSTANCE: invention relates to a novel 2-{4-[(E)-2-(4-ethoxyphenyl)vinyl]phenoxy}-N,N,N-trimethylethanamine bromide, having properties of a surface-active photosensitiser with a structure which enables to alter excitability of heart and neural tissue by blocking ion channels of cells. The compound facilitates selective irreversible blocking of ion channels of only those cells exposed to UV radiation in the presence of said compound. In particular, the compound can be used in pre-clinical studies of antiarrhythmic drugs when creating various novel model systems. The compound has the structural formulaEFFECT: compound has low toxicity.5 dwg, 1 tbl, 1 ex