发明名称 |
MICROORGANISMS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING 1,2-PROPANEDIOL |
摘要 |
Provided herein is a non-naturally occurring microbial organism (NNOMO) having a methanol metabolic pathway (MMP) that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 1,2-propanediol (1,2-PDO), n- propanol (n-PrOH), 1,3-propanediol (1,3-PDO) or glycerol. Also provided herein are methods for using such an organism to produce 1,2-PDO, n-PrOH, 1,3-PDO or glycerol. |
申请公布号 |
WO2014071286(A1) |
申请公布日期 |
2014.05.08 |
申请号 |
WO2013US68254 |
申请日期 |
2013.11.04 |
申请人 |
GENOMATICA, INC. |
发明人 |
BURGARD, ANTHONY, P.;OSTERHOUT, ROBIN, E.;VAN DIEN, STEPHEN, J.;TRACEWELL, CARA, ANN;PHARKYA, PRITI;ANDRE, STEFAN |
分类号 |
C07C31/22;C12P7/20 |
主分类号 |
C07C31/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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