STABLE TRANSDERMAL PHARMACEUTICAL DRUG DELIVERY SYSTEM COMPRISING DICLOFENAC

摘要

The present invention relates to stable transdermal pharmaceutical drug delivery system of diclofenac or a pharmaceutically acceptable salt thereof. In particular, the present invention relates to a stable transdermal pharmaceutical drug delivery system of diclofenac or a pharmaceutically acceptable salt thereof which is free of any penetration enhancer. Further, the transdermal pharmaceutical drug delivery system may be free from any antioxidant. More particularly, the present invention relates to stable transdermal pharmaceutical drug delivery system of diclofenac or a pharmaceutically acceptable salt thereof, which provides an enhanced absorption of drug through skin, has a flexible backing, shows longer duration of action, and inhibits crystal formation of drug.substance during storage period.