| 发明名称 |
Stable and soluble antibodies inhibiting TNFalpha |
| 摘要 |
The present invention relates to particularly stable and soluble scFv antibodies and Fab fragments specific for TNF, which comprise specific light chain and heavy chain sequences that are optimized for stability, solubility, |
| 申请公布号 |
AU2009264564(B2) |
申请公布日期 |
2014.05.08 |
| 申请号 |
AU20090264564 |
申请日期 |
2009.06.25 |
| 申请人 |
ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC |
发明人 |
URECH, DAVID;GUNDE, TEA;BORRAS, LEONARDO |
| 分类号 |
C07K16/24;A61K39/395;C12N15/13 |
主分类号 |
C07K16/24 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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