发明名称 CASPOFUNGIN OR SALTS THEREOF WITH HIGH PURITY, AS WELL AS PREPARATION METHOD AND USE THEREOF
摘要 Disclosed are a high purity of caspofungin or salts thereof, and a preparation method thereof, and use thereof. Disclosed are a caspofungin or salts thereof with low solvent residue and hyposaline, and a preparation process comprising: dissolving a crude product of caspofungin or slats thereof into a system of water and acetic acid, them mixing with a first organic solvent ethyl alcohol, subsequently mixing with a second organic solvent ethyl acetate, then being subject to filtration and drying together with water, to obtain caspofungin or salts thereof with high stability, low solvent residue and hyposaline.
申请公布号 US2014128315(A1) 申请公布日期 2014.05.08
申请号 US201214113296 申请日期 2012.04.20
申请人 HE BINGMING;LI MING;TANG ZHIJUN;JI XIAOMING;SHANGHAI TECHWELL BIOPHARMACEUTICAL CO., LTD. 发明人 HE BINGMING;LI MING;TANG ZHIJUN;JI XIAOMING
分类号 A61K38/12;A61K31/19 主分类号 A61K38/12
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