发明名称 |
MECHANICAL PHENOTYPING OF SINGLE CELLS: HIGH THROUGHPUT QUANTITATIVE DETECTION AND SORTING |
摘要 |
This invention provides methods and devices for the high-throughput characterization of the mechanical properties of cells or particles. In certain embodiments the devices comprise a microfluidic channel comprising: an oscillating element on a first side of said channel; and a detecting element on a second side of said channel opposite said oscillating element, wherein said detecting element is configured to detect a force transmitted through a cell or microparticle by said oscillating element. In certain embodiments the devices comprise a microfluidic channel comprising an integrated oscillator and sensor element on one first side of said channel, wherein said sensor is configured to detect a force transmitted through a cell or microparticle by said oscillator. |
申请公布号 |
US2014128285(A1) |
申请公布日期 |
2014.05.08 |
申请号 |
US201313802684 |
申请日期 |
2013.03.13 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ROWAT AMY;HOELZLE DAVID J.;CHAN CLARA |
分类号 |
G01N33/483;G01N33/50 |
主分类号 |
G01N33/483 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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