REGULATED GENE EXPRESSION SYSTEMS AND CONSTRUCTS THEREOF
摘要
The present disclosure is directed to compositions and methods for nitrogen sensitive regulation of expression of a transcribable nucleic acid molecule. One aspect provides a nitrogen-sensitive expression system that includes a transcription factor region comprising an NtcA binding site and a core promoter region comprising a RuBisCo promoter or a variant or a functional fragment thereof. Another aspect provides a method of transforming a host cell with an expression system. Also provided are expression cassettes, transformed host cells, and kits.
申请公布号
WO2012135137(A3)
申请公布日期
2014.05.08
申请号
WO2012US30602
申请日期
2012.03.26
申请人
PROTERRO, INC.;TURNER, ROBERT J.;SERSHON, VALERIE;AIKENS, JOHN;HOLZLE, DENISE
发明人
TURNER, ROBERT J.;SERSHON, VALERIE;AIKENS, JOHN;HOLZLE, DENISE