发明名称 |
SELECTIVE AMPLIFICATION AND REAL-TIME PCR DETECTION OF RARE MUTATIONS |
摘要 |
Provided herein are methods and kits for the improved detection of rare mutations within a high background. Exemplary embodiments relate to kits and methods that include amplification primers, a blocking oligonucleotide, and one or more allele-specific detector probes, useful in the specific detection of rare allelic variants or mutations. |
申请公布号 |
WO2014070946(A1) |
申请公布日期 |
2014.05.08 |
申请号 |
WO2013US67604 |
申请日期 |
2013.10.30 |
申请人 |
BECTON, DICKINSON AND COMPANY |
发明人 |
NADEAU, JAMES G.;HELLYER, TOBIN J. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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