发明名称 |
RELAXIN FUSION POLYPEPTIDES AND USES THEREOF |
摘要 |
The present invention provides Relaxin fusion polypeptides A-L-B with a non-wild type array of the Relaxin A-chain and Relaxin B-chain, wherein the A- and B-chains are connected by a linker peptide. The invention further provides Relaxin fusion polypeptides with extended half-life. Furthermore, the invention provides nucleic acid sequences encoding the foregoing fusion polypeptides, vectors containing the same, pharmaceutical compositions and medical use of such fusion polypeptides. |
申请公布号 |
KR20140054009(A) |
申请公布日期 |
2014.05.08 |
申请号 |
KR20147002543 |
申请日期 |
2012.06.29 |
申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
WILMEN ANDREAS;HAUPTS ULRICH;FREIBERG CHRISTOPH;TRAUTWEIN MARK;LINDEN LARS;LEINEWEBER KIRSTEN;TINEL HANNA |
分类号 |
C07K19/00;A61K38/22;C07K14/64 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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