HISTAMINE RECEPTOR ANTAGONIST COMPOSITION CONTAINING GAMMA ORYZANOL AS ACTIVE INGREDIENT

摘要

The present invention provides a novel use of gamma oryzanol as a histamine receptor antagonist. Gamma oryzanol is used as a natural antihistamine and can be used for preventing or treating allergic rhinitis, inflammatory bowel diseases, asthma, bronchitis, vomiting, stomach and duodenal ulcer, gastoesophegal reflux diseases, sleep disturbance, anxiety, and depression, and has the advantages of further reducing sleep latency, increasing sleep time, and increasing non-REM sleep time. Gamma oryzanol is a natural product derived from rice bran and does not cause side effects such as cognitive impairment, resistance, or dependence even after long-term use.