发明名称 |
COMPOSITION AND METHOD FOR DELIVERY OF HYDROPHOBIC ACTIVE AGENTS |
摘要 |
Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed. |
申请公布号 |
CA2890205(A1) |
申请公布日期 |
2014.05.08 |
申请号 |
CA20132890205 |
申请日期 |
2013.11.05 |
申请人 |
SURMODICS, INC. |
发明人 |
VENTURA, JOSEPH;WADMAN, SHANNON;SLAGER, JORAM;MCGONIGLE, JOSEPH SCHMIDT;HERGENROTHER, ROBERT W. |
分类号 |
A61K47/34;A61K31/337;A61L31/10;A61L31/16;A61L33/00 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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