| 发明名称 |
CONTROLLED HNO RELEASE THROUGH INTRAMOLECULAR CYCLIZATION-ELIMINATION |
| 摘要 |
<p>Protected HNO donors designed to undergo non-enzymatic release at neutral pH via an intramolecular cyclization-elimination are disclosed. The rate of cyclization, and therefore HNO release, can be controlled by substituents and chain length. Thus, biologically useful HNO donors having tunable HNO release rates are provided.</p> |
| 申请公布号 |
WO2014070919(A1) |
申请公布日期 |
2014.05.08 |
| 申请号 |
WO2013US67558 |
申请日期 |
2013.10.30 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
TOSCANO, JOHN P.;SUTTON, ART D. |
| 分类号 |
C07C311/48;A61P9/10 |
主分类号 |
C07C311/48 |
| 代理机构 |
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