发明名称 |
CHIMERIC VACCINE ANTIGENS AGAINTS HEPATITIS C VIRUS |
摘要 |
The invention relates to chimeric vaccine antigens against hepatitis C virus (HCV), comprising selected regions of different antigens of said virus, which are placed in a pre-determined order inside the polypeptide. In addition, said chimeric antigens can include artificially-formed specific epitopes for auxiliary T cells. The chimeric antigens, and the resulting vaccine compositions, are suitable for use in medicine and the pharmaceutical industry, as well as being suitable for prophylactic and/or therapeutic use against HCV. The vaccine compositions of the invention generate a powerful, broad-spectrum immune response against different antigens of the virus, with a minimum number of components. |
申请公布号 |
CA2901346(A1) |
申请公布日期 |
2014.05.08 |
申请号 |
CA20132901346 |
申请日期 |
2013.10.28 |
申请人 |
CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA |
发明人 |
DUENAS CARRERA, SANTIAGO;AGUILAR NORIEGA, DAYLEN;AMADOR CANIZARES, YALENA;ALVAREZ-LAJONCHERE PONCE DE LEON, LIZ;MARTINEZ DONATO, GILLIAN;GONZALEZ BLANCO, SONIA |
分类号 |
A61K39/12 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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地址 |
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