Biodegradable intravitreal tyrosine kinase inhibitor implants

摘要

C /NRPo, b CC0ZGk1XW477.1 DOC-l 01./x2011 BIODEGRADABLE INTRAVITREAL TYROSINE KINASE INHIBITOR Abstract Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants can be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as posterior ocular conditions.