发明名称 SULFONAMIDES AS HIV PROTEASE INHIBITORS
摘要 <p>Compounds of Formula I are disclosed: wherein L, A, R1, R2, R3A, R3B, R4A, R4B, R5, R6 and R7 are defined herein. The compounds encompassed by Formula I include compounds which are HIV protease inhibitors and other compounds which can be metabolized in vivo to HIV protease inhibitors. The compounds and their pharmaceutically acceptable salts are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.</p>
申请公布号 EP2632908(A4) 申请公布日期 2014.05.07
申请号 EP20110835401 申请日期 2011.10.27
申请人 MERCK CANADA INC. 发明人 MORADEI, OSCAR, M.;CRANE, SHELDON;MCKAY, DANIEL, J.;LEBRUN, MARIE-EVE;TRUONG, VOUY LINH
分类号 C07D277/62;A61K31/27;A61K31/415;A61K31/421;A61K31/426;A61K31/427;A61K31/4439;A61K31/505;A61K31/506;A61P31/18;C07C311/29;C07C311/41;C07C317/40;C07C323/49;C07D231/12;C07D261/08;C07D417/12;C07D417/14 主分类号 C07D277/62
代理机构 代理人
主权项
地址