发明名称 |
GABA AGONISTS IN THE TREATMENT OF DISORDERS ASSOCIATED WITH METABOLIC SYNDROME AND GABA COMBINATIONS IN TREATMENT OR PROPHYLAXIS OF TYPE I DIABETES |
摘要 |
In certain embodiments methods are provided for the therapeutic or prophylactic amelioration of one or more symptoms or disorders associated with metabolic syndrome. In various embodiments the methods involve administering to a subject in need thereof, a GABA receptor agonist, in an amount sufficient to ameliorate said one or more symptoms. In certain embodiments methods are provided for the prophylaxis or treatment of type I diabetes and related pathologies that involve the use of GABA or GABA agonists in combination with certain other compounds (e.g., one more antigens (e.g., GAD) that have a therapeutic effect in type I diabetes and/or an anti-CD3 antibody, an anti-CD20 antibody, exendin-4, and/or or a pro-insulin therapeutic). |
申请公布号 |
EP2621282(A4) |
申请公布日期 |
2014.05.07 |
申请号 |
EP20110833060 |
申请日期 |
2011.09.28 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
KAUFMAN, DANIEL;TIAN, JIDE |
分类号 |
A01N57/00;A01N37/00;A61K31/19;A61K31/197;A61K31/4465;A61K31/66;A61K38/20;A61K39/00;A61K39/39;A61K45/06;A61P3/08;A61P3/10 |
主分类号 |
A01N57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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